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Resin must be selected considering the following factors:
- Strong base resins have higher loading capacity and rate. However selectivity is poor and elution is difficult.
- Weak base resins are selective and elution is easy, but its loading rate is slow.
- Strong base resins are cheaper than weak base resins.
- Weak base resins offer a good elution rate and the elution reagents are cheaper than the reagents employed in strong base resins.
- Resins to be chosen must be consider the resistance to osmotic shock in order to don’t alter its structure.
- Resin must have an appropriate porosity.
- Resin must not be soluble.
- Resins physical resistance is an important aspect because there are some losses by mechanical agitation, pumping, and screening.
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